The Thames River was a river in London, England of United Kingdom.

It is seen in 2011 where Mr. Issacs arrived in London at the Empire Grand Hotel to recruit the Saudi Prince to boarding the Arks, with his family, in order to survive the world's ending in 2012. During the 2012 apocalypse, the Thames was hit by massive earthquakes, causing major damage to the waters and killing people on boats or ferries. The Thames River is currently submerged underwater when a megatsunami swept away the ruined and devastated United Kingdom during the Worldwide Flooding.

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