San Francisco was a hilly city in northern California on the tip of a peninsula surrounded by the Pacific Ocean and San Francisco Bay. It was known for its year-round fog, iconic Golden Gate Bridge, cable cars and colorful Victorian houses. The Financial District's Transamerica Pyramid is its most distinctive skyscraper. In the bay sits Alcatraz Island, site of the notorious former prison.
It is only shown when the Genesis has an incident on the dock it is on, which takes place in the Bay Area. San Francisco was most likely destroyed by earthquakes then swept by megatsunami during the 2012 apocalypse.
- San Francisco at Wikipedia